Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

THPO / TPO / Thrombopoietin

thrombopoietin

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

Gene Name: thrombopoietin
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: THPO, C-mpl ligand, MGDF, MPL ligand, THCYT1, Thrombopoietin nirs variant 1, MKCSF, MPLLG, Thrombopoietin
Target Sequences: NM_000460 NP_000451.1 P40225

☰ Filters
Products
Proteins (31)
Over-Expression Lysate (4)
Recombinant (27)
THPO / TPO / Thrombopoietin (31)
Animal-free (3)
No (31)
6His, C-terminus (1)
6His, N-terminus (2)
6His, N-terminus + 6His, C-terminus (4)
6His-SUMO, N-terminus (1)
GST (2)
His, N-Terminal (3)
His-GST (2)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (14)
Mouse (11)
Rat (4)
293T Cells (2)
CHO Cells (2)
E. coli (17)
HEK 293 Cells (2)
Human Cells (4)
Mammalian Cells (3)
Wheat Germ Extract (1)
Purified (11)
Low endotoxin level (17)
Biologically active (13)
Animal-free (3)
Select
Human Cells
6His, N-terminus + 6His, C-terminus
Biologically active
Less than 1 EU/µg (determined by LAL method).
75-90 kDa
10 µg/$402; 1 mg/$3,412; 50 µg/$879; 500 µg/$2,449
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
18.6 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$281; 10 µg/$369
Select
E. coli
GST
46 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
30-80 kDa (SDS-PAGE)
50 µg/$432; 10 µg/$296; 1 mg/$2,171
THPO / TPO / Thrombopoietin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
37.8 kDa
20 µg/$150
THPO / TPO / Thrombopoietin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
37.82 kDa
20 µg/$150
THPO / TPO / Thrombopoietin Protein
Select
E. coli
None
Biologically active
18.7 kDa
10 µg/$388; 100 µg/$1,277; 500 µg/$2,501
THPO / TPO / Thrombopoietin Protein - Recombinant Thrombopoietin By SDS-PAGE
Select
E. coli
His-GST
67.4 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
THPO / TPO / Thrombopoietin Protein - Recombinant Thrombopoietin By SDS-PAGE
Select
E. coli
His-GST
61.8 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
THPO / TPO / Thrombopoietin Protein - Recombinant Thrombopoietin By SDS-PAGE
Select
E. coli
His-T7
29.8 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
18.7 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$281; 10 µg/$369
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
18.7 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$282; 10 µg/$370
Select
Human Cells
6His, N-terminus + 6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
37.3kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.4kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
THPO / TPO / Thrombopoietin Protein - 12.5% SDS-PAGE of human THPO stained with Coomassie Blue
Select
Wheat Germ Extract
GST
63.8 kDa
2 µg/$439
THPO / TPO / Thrombopoietin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
37.82 kDa
100 µg/$494
THPO / TPO / Thrombopoietin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
37.8 kDa
100 µg/$494
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~35 kDa
1 mg/$3,855
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~19 kDa
10 µg/$432; 1 mg/$6,871
THPO / TPO / Thrombopoietin Protein - Recombinant Thyroid Peroxidase (TPO) by SDS-PAGE
Select
E. coli
His, N-Terminal
25.4kDa
10 µg/$268; 50 µg/$362; 200 µg/$722; 100 µg/$577; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.4kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
THPO / TPO / Thrombopoietin Protein - Recombinant Thrombopoietin (TPO) by SDS-PAGE
Select
E. coli
His, N-Terminal
29.2kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Viewing 1-25 of 31 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).