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THPO / TPO / Thrombopoietin
thrombopoietin
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.
| Gene Name: | thrombopoietin |
| Family/Subfamily: | Hormone , not assigned-Hormone |
| Synonyms: | THPO, C-mpl ligand, MGDF, MPL ligand, THCYT1, Thrombopoietin nirs variant 1, MKCSF, MPLLG, Thrombopoietin |
| Target Sequences: | NM_000460 NP_000451.1 P40225 |
☰ Filters
Products
Proteins
(31)
Type
Over-Expression Lysate
(4)
Recombinant
(27)
Target
THPO / TPO / Thrombopoietin
(31)
Format
Animal-free
(3)
Publications
No
(31)
Tag
6His, C-terminus
(1)
6His, N-terminus
(2)
6His, N-terminus + 6His, C-terminus
(4)
6His-SUMO, N-terminus
(1)
GST
(2)
His, N-Terminal
(3)
His-GST
(2)
His-T7
(1)
Myc-DDK (Flag)
(4)
Species
Human
(14)
Mouse
(11)
Rat
(4)
Source
293T Cells
(2)
CHO Cells
(2)
E. coli
(17)
HEK 293 Cells
(2)
Human Cells
(4)
Mammalian Cells
(3)
Wheat Germ Extract
(1)
Purification
Purified
(11)
Low Endotoxin Level
Low endotoxin level
(17)
Biologically Active
Biologically active
(13)
Animal-free
Animal-free
(3)
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
18.6 kDa
2 µg/$268; 10 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$281; 10 µg/$369
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
18.7 kDa
2 µg/$268; 10 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$281; 10 µg/$369
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
18.7 kDa
2 µg/$268; 10 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$282; 10 µg/$370
E. coli
None
Biologically active
18.7 kDa
10 µg/$388; 100 µg/$1,277; 500 µg/$2,501
E. coli
His-GST
67.4 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
E. coli
His-GST
61.8 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
E. coli
His-T7
29.8 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
E. coli
GST
46 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Wheat Germ Extract
GST
63.8 kDa
2 µg/$439
293T Cells
Myc-DDK (Flag)
37.82 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
37.8 kDa
20 µg/$150
E. coli
His, N-Terminal
29.2kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Mouse THPO / TPO / Thrombopoietin Protein (Recombinant His, N-Terminal) (His402-Val558) - LS-G133043
E. coli
His, N-Terminal
19.5kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838
E. coli
His, N-Terminal
25.4kDa
10 µg/$268; 50 µg/$362; 200 µg/$722; 100 µg/$577; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
HEK 293 Cells
Myc-DDK (Flag)
37.8 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
37.82 kDa
100 µg/$494
E. coli
6His-SUMO, N-terminus
34.7 kDa
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Mammalian Cells
6His, N-terminus + 6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
37.3 kDa
50 µg/$698; 10 µg/$356; 1 mg/$2,837; 500 µg/$1,987
CHO Cells
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
Predicted molecular mass of approximately 35.5 kD. The protein migrates at about 40 kD in DTT-reducing conditions and about 35 kD in non-reducing condition by SDS-PAGE.The N-terminal amino acid is Ser.
10 µg/$352; 25 µg/$459; 100 µg/$1,049
Mammalian Cells
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.4 kDa
10 µg/$317; 50 µg/$524
Mammalian Cells
6His, N-terminus + 6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
37.3 kDa
10 µg/$317; 50 µg/$524
Human Cells
6His, N-terminus + 6His, C-terminus
Biologically active
Less than 1 EU/µg (determined by LAL method).
75-90 kDa
10 µg/$402; 1 mg/$3,412; 50 µg/$879; 500 µg/$2,449
Viewing 1-25
of 31
product results
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