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CDH1 / E Cadherin

cadherin 1, type 1, E-cadherin (epithelial)

CDH1 / E Cadherin is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Gene Name: cadherin 1, type 1, E-cadherin (epithelial)
Family/Subfamily: Cadherin , not assigned-Cadherin
Synonyms: CDH1, CD324, CDHE, Cell-CAM 120/80, E Cadherin, E-Cadherin, ECAD, Epithelial cadherin, Arc-1, UVO, Cadherin-1, CAM 120/80, CD324 antigen, LCAM, Uvomorulin
Target Sequences: NM_004360 NP_004351.1 P12830

Publications (4)

1
Expression, purification, and functional characterization of recombinant PTD-SARA. Huang C, Du R, Zhang P, Meng H, Jia H, Song Y, Li M, Zhang Y, Sun S. Acta biochimica et biophysica Sinica. 2011 43:110-7. (ICC) [PubMed:21266541]
2
Comparison of Different In Vivo Incubation Sites to Produce Tissue-Engineered Small Intestine. Liu Y, Cromeens BP, Wang Y, Fisher K, Johnson J, Chakroff J, Besner GE. Tissue engineering. Part A. 2018 July;4:1138-1147. [Full Text Article] [PubMed:29383981] [PMC:PMC6033308] Related Antibodies: LS-B12414.
3
Benefit of Physiologically Variable Over Pressure-Controlled Ventilation in a Model of Chronic Obstructive Pulmonary Disease: A Randomized Study. Andre Dos Santos Rocha, Roberta Südy, Davide Bizzotto, Miklos Kassai, Tania Carvalho, Raffaele L Dellacà, Ferenc Peták, Walid Habre. Frontiers in physiology. 2021 Jan;11:625777. [Full Text Article] [PubMed:33519528] [PMC:PMC7839245]
4
Physiologically variable ventilation in a rabbit model of asthma exacerbation. André Dos Santos Rocha, Roberta Südy, Ferenc Peták, Walid Habre. British journal of anaesthesia. 2020 December;125:1107-1116. [Full Text Article] [PubMed:33070949]
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CDH1 / E Cadherin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CDH1 / E Cadherin Goat anti-Human Polyclonal Antibody
Mouse, Dog, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
300 µg/$460
CDH1 / E Cadherin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CDH1 / E Cadherin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Zebrafish, Pig, Rat, Rabbit, Dog, Bovine, Human, Monkey
Flo, ICC, IF, IHC-P, IP, WB
Unconjugated
50 µl/$460
CDH1 / E Cadherin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
CDH1 / E Cadherin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CDH1 / E Cadherin Antibody - Anti-E Cadherin antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.
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CDH1 / E Cadherin Mouse anti-Human Monoclonal (3F4) Antibody
Human
ELISA, IHC, IHC-P, PLA, WB
Unconjugated
50 µg/$440
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CDH1 / E Cadherin Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, Func, IF, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$851
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CDH1 / E Cadherin Rat anti-Mouse Monoclonal (ECCD-2) Antibody
Mouse, Human
Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$890
CDH1 / E Cadherin Antibody - Anti-E Cadherin antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Cancer Pathology
Cancer
CDH1 / E Cadherin Rabbit anti-Human Polyclonal (aa503-552) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CDH1 / E Cadherin Antibody - Western blot of E-cadherin antibody
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CDH1 / E Cadherin Rabbit anti-Human Polyclonal (810-890 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CDH1 / E Cadherin ELISA Kit
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Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
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E. coli
6His, N-terminus
64.42 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CDH1 / E Cadherin Antibody - Anti-E Cadherin antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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CDH1 / E Cadherin Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
CDH1 / E Cadherin Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
CDH1 / E Cadherin Mouse anti-Human Monoclonal (813CT11.1.3) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
CDH1 / E Cadherin Antibody - Western blot using CDH1 mouse monoclonal antibody against LNCAP (1),A431 (2), DU145 (3), PC-3 (4), MCF-7 (5), PC-12 (6), NIH/3T3 (7), C6 (8) and COS7 (9) cell lysate.
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CDH1 / E Cadherin Mouse anti-Human Monoclonal (7H12) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$435
CDH1 / E Cadherin Antibody - E Cadherin antibody IHC-paraffin. IHC(P): Human Placenta Tissue.
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CDH1 / E Cadherin Rabbit anti-Human Polyclonal (aa286-703) Antibody
Dog, Sheep, Bovine, Rat, Pig, Horse, Bat, Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CDH1 / E Cadherin Protein - Recombinant Cadherin, Epithelial By SDS-PAGE
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E. coli
His, N-Terminal
20.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
CDH1 / E Cadherin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
CDH1 / E Cadherin Mouse anti-Human Recombinant Monoclonal (rCDH1/1525) Antibody
Human
IF, IHC-P, WB
Unconjugated
100 µg/$525
CDH1 / E Cadherin Antibody - Western blot of CDH1 Antibody in 293 cell line lysates (35 ug/lane). CDH1 (arrow) was detected using the purified antibody.
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CDH1 / E Cadherin Rabbit anti-Human Polyclonal (aa160-189) Antibody
Mouse, Human
Flo, WB
Unconjugated
400 µl/$393
CDH1 / E Cadherin Antibody - Western blot of CDH1 Antibody in A375 cell line lysates (35 ug/lane). CDH1 (arrow) was detected using the purified antibody.
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CDH1 / E Cadherin Rabbit anti-Human Polyclonal (aa833-862) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
CDH1 / E Cadherin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CDH1 / E Cadherin Rabbit anti-Human Recombinant Monoclonal (CDH1/2208R) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
50 µg/$460
CDH1 / E Cadherin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CDH1 / E Cadherin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC-P, WB
Unconjugated
50 µg/$460
CDH1 / E Cadherin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CDH1 / E Cadherin Mouse anti-Human Monoclonal (aa373-621) Antibody
Human
IHC-P, WB
Unconjugated
50 µl/$460
Select
CDH1 / E Cadherin Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, IHC-Fr, IHC-P, Inhb, WB
Unconjugated
100 µg/$550
CDH1 / E Cadherin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH1.
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CDH1 / E Cadherin Mouse anti-Human Monoclonal (Extracellular Domain) (OTI3C11) Antibody
Human
WB
Unconjugated
100 µl/$434
Select
CDH1 / E Cadherin Mouse anti-Human Monoclonal (67A4) Antibody
Human
Flo, ICC, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$323
Select
CDH1 / E Cadherin Mouse anti-Human Monoclonal (FITC) (67A4) Antibody
Human
Flo
FITC Conjugated
100 Tests/$337
Viewing 1-25 of 315 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).