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IL7

interleukin 7

IL7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Gene Name: interleukin 7
Family/Subfamily: IL-7/ IL-9 , not assigned-IL-7/ IL-9
Synonyms: IL7, IL-7, Interleukin-7, Interleukin 7
Target Sequences: NM_000880 NP_000871.1 P13232

Publications (1)

1
Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Nicolas Severe, Nezihi Murat Karabacak, Karin Gustafsson, Ninib Baryawno, Gabriel Courties, Youmna Kfoury, Konstantinos D Kokkaliaris, Catherine Rhee, Dongjun Lee, Elizabeth W Scadden, Juan Esteban Garcia-Robledo, Thomas Brouse, Matthias Nahrendorf, Mehmet Toner, David T Scadden. Cell stem cell. 2019 October;25:570-583.e7. [Full Text Article] [PubMed:31279774] [PMC:PMC6778015] Related Antibodies: LS-B14351.

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Antibodies (75)
Primary (75)
IL7 (75)
Human (54)
Mouse (29)
Rat (8)
Pig (3)
IHC (6)
IHC-P (2)
WB (63)
ELISA (34)
FLISA (2)
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IP (4)
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Peptide-ELISA (1)
SwELISA (2)
rabbit (62)
mouse (4)
rat (9)
Product Group
IHCPlus (1)
IgG (28)
IgG1 (2)
IgG1,k (4)
IgG2a,k (4)
IgG2b (1)
monoclonal mc (13)
polyclonal pc (62)
06 (1)
075 (1)
20 (1)
BVD10-11C10 (2)
BVD10-40F6 (3)
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Azide-free (2)
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Cy3 Conjugated (2)
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FITC Conjugated (6)
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PE Conjugated (5)
Preservative Free (3)
Unconjugated (38)
aa26-177 (10)
aa26-154 (9)
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Internal (1)
aa26-42 (1)
No (74)
Yes (1)
IL7 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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IL7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
IL7 Antibody - Western Blot (non-reducing) of Interleukin 7 / IL-7 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL7 Antibody - Western Blot (non-reducing) of Interleukin 7 / IL-7 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
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IL7 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, Func, Neut, WB
Unconjugated
100 µg/$801
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IL7 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated
100 µl/$1,024
IL7 Antibody - IL7 antibody. IHC(P): Mouse Spleen Tissue.
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IL7 Rabbit anti-Mouse Polyclonal (aa26-42) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL7 Antibody - Western Blot (non-reducing) of Interleukin 7 / IL-7 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL7 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL7 Antibody - Western Blot (non-reducing) of Interleukin 7 / IL-7 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL7 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
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IL7 Rat anti-Human Monoclonal (Azide-free) Antibody
Human
ELISA, IP, Neut, WB
Unconjugated, Azide-free
500 µg/$588
IL7 Antibody - anti-Human IL-7 antibody shows detection of a band ~17 kDa in size corresponding to recombinant human IL-7. The identity of the faint higher molecular weight band may represent a homodimer. Molecular weight markers are also shown (left). After transfer, the membrane was blocked overnight with 3% BSA in TBS followed by reaction with primary antibody at a 1:1,000 dilution. Detection occurred using peroxidase conjugated anti-Rabbit IgG secondary antibody diluted 1:40,000 in blocking buffer for 30 min at RT followed by reaction with FemtoMax™ chemiluminescent substrate. Image was captured using VersaDoc™ MP 4000 imaging system (Bio-Rad).
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IL7 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
100 µg/$552
IL7 Antibody - Biotin Rabbit Anti-Human IL-7 Antibody - Western Blot. Western Blot showing detection of Human IL-7. 50 ng of Human IL-7 (Lane 1) was run on a 4-20% gel and transferred to 0.45 micron nitrocellulose. After blocking with 5% Blotto (B501-0500) 30 min at 20?, Anti-Human IL-7 (RABBIT) Antibody Biotin Conjugated Anti-Human IL-7 (RABBIT) Antibody Biotin Conjugated - 209-406-B94 secondary antibody was used at 1:1000 in Blocking Buffer for Fluorescent Western Blot (p/n MB-070). HRP Streptavidin (p/n S000-03) was used at 1:40000 in MB-070 for 30 min at 20? and imaged using the Bio-Rad VersaDoc 4000 MP. Arrow indicates correct 17 kD molecular weight position expected for Human IL-7. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
100 µg/$552
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IL7 Rat anti-Human Monoclonal (BVD10-40F6) Antibody
Human
IP, SwELISA, WB
Unconjugated
0.5 mg/$431
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IL7 Rat anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
500 µg/$563
IL7 Antibody - Western blot of recombinant IL7.
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IL7 Rabbit anti-Human Polyclonal (aa26-177) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$325; 200 µl/$375; 500 µl/$539; 1 ml/$632; 2 ml/$867; 5 ml/$1,439
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IL7 Rabbit anti-Rat Monoclonal (Preservative Free) (075) Antibody
Rat
ELISA
Unconjugated, Preservative Free
100 µl/$412
IL7 Antibody - 1:100 staining human pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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IL7 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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IL7 Rat anti-Human Monoclonal Antibody
Human
ELISA, IP, WB
Unconjugated
500 µg/$563
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IL7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Func, WB
Unconjugated
100 µg/$748
IL7 Antibody - WB of IL7 antibody. Lane 1: Recombinant Human IL-7 Protein 10ng. Lane 2: Recombinant Human IL-7 Protein 5ng. Lane 3: Recombinant Human IL-7 Protein 2.5ng. Lane 4: Recombinant Human IL-7 Protein 1.25ng..
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IL7 Rabbit anti-Human Polyclonal (aa26-177) Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
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IL7 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$326
IL7 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using IL7 Polyclonal Antibody at dilution of 1:30(×200)
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IL7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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IL7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$558
IL7 Antibody - IL7 antibody Western blot. All lanes: Anti IL7 at 0.5 ug/ml. WB: K562 Whole Cell Lysate at 40 ug. Predicted band size: 20 kD. Observed band size: 75 kD.
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IL7 Rabbit anti-Human Polyclonal (aa26-177) Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL7 Antibody - Anti-IL-7 Antibody - Western Blot. anti-Human IL-7 antibody shows detection of a band ~17 kD in size corresponding to recombinant human IL-7. The identity of the faint higher molecular weight band may represent a homodimer. Molecular weight markers are also shown (left). After transfer, the membrane was blocked overnight with 3% BSA in TBS followed by reaction with primary antibody at a 1:1000 dilution. Detection occurred using peroxidase conjugated anti-Rabbit IgG (LS-C60865) secondary antibody diluted 1:40000 in blocking buffer (p/n MB-070) for 30 min at RT followed by reaction with FemtoMax chemiluminescent substrate. Image was captured using VersaDoc MP 4000 imaging system (Bio-Rad).
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IL7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$567
IL7 Antibody
Select
IL7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$575
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).