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TJP1 / ZO-1
tight junction protein 1
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
| Gene Name: | tight junction protein 1 |
| Family/Subfamily: | Occludin , Not assigned-Occludin |
| Synonyms: | TJP1, ZO-1, Zona occludens protein 1, Zona occludens 1, Zonula occludens protein 1, Tight junction protein 1, ZO1, Tight junction protein ZO-1, Zonula occludens 1 protein |
| Target Sequences: | NM_003257 NP_003248.3 Q07157 |
Publications (11)
1
A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells. Malchenko S, Sredni ST, Hashimoto H, Kasai A, Nagayasu K, Xie J, Margaryan NV, Seiriki K, Lulla RR, Seftor RE, Pachman LM, Meltzer HY, Hendrix MJ, Soares MB. PloS one. 2015 10:e0121707. (ICC, IHC-P; Human)
[Full Text Article]
[PubMed:25826270]
[PMC:PMC4380339]
2
Tricellulin Expression and its Deletion Effects in the Endolymphatic Sac. Ai Matsubara, Takenori Miyashita, Ryuhei Inamoto, Hirofumi Sakaguchi, Toru Kamitani, Nozomu Mori, Hiroshi Hoshikawa. The journal of international advanced otology. 2018 August;14:312-316. [Full Text Article]
[PubMed:30100545]
[PMC:PMC6354451]
Related Antibodies: LS-C124822.
3
Reversal of cigarette smoke extract-induced sinonasal epithelial cell barrier dysfunction through Nrf2 Activation. Anuj Tharakan, Ashleigh A Halderman, Andrew P Lane, Shyam Biswal, Murugappan Ramanathan Jr. International forum of allergy & rhinology. 2016 November;6:1145-1150. [Full Text Article]
[PubMed:27580429]
[PMC:PMC5097009]
Related Antibodies: LS-C354905.
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TJP1 / ZO-1
(97)
Reactivity
Human
(55)
Mouse
(35)
Rat
(28)
Bat
(3)
Chicken
(1)
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(6)
Dog
(14)
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(3)
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(13)
Horse
(3)
Monkey
(9)
Pig
(4)
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(34)
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(24)
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(91)
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(6)
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(3)
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(4)
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(13)
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(13)
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(7)
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(1)
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(1)
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His-T7
(1)
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(4)
Species
Dog
(1)
Human
(5)
Rat
(1)
Source
293T Cells
(1)
E. coli
(3)
HEK 293 Cells
(3)
Wheat Germ Extract
(1)
Cancer
TJP1 / ZO-1 Goat anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
300 µg/$460
Cancer
TJP1 / ZO-1 Rabbit anti-Human Polyclonal (aa935-984) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
TJP1 / ZO-1 Rabbit anti-Human Polyclonal (aa463-1109) Antibody
Mouse, Dog, Guinea pig, Rat, Human
ELISA, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µg/$485
Cancer
TJP1 / ZO-1 Rabbit anti-Human Polyclonal (aa1-296) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
TJP1 / ZO-1 Rat anti-Mouse Monoclonal Antibody
Mouse
IHC, IP, WB
Unconjugated
100 µg/$872
TJP1 / ZO-1 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat
WB
Unconjugated
100 µl/$424
TJP1 / ZO-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Pig, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TJP1 / ZO-1 Mouse anti-Human Monoclonal (aa334-634) (AF594) (ZO1-1A12) Antibody
Dog, Human
ELISA, ICC, IF, WB
AF594 Conjugated
100 µg/$566
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$730
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
Sandwich
96-Well Microplate
Mouse
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
E. coli
His-T7
24.7 kDa
10 µg/$285; 50 µg/$470; 200 µg/$937; 1 mg/$2,063; 5 mg/$3,277; 2 mg/$2,252
E. coli
His-S
56.4 kDa
10 µg/$289; 50 µg/$490; 100 µg/$782; 200 µg/$977; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304
Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Sandwich
96-Well Strip Plate
Chicken
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
293T Cells
Myc-DDK (Flag)
195.3 kDa
20 µg/$215
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$783
Sandwich
96-Well Strip Plate
Rabbit
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
TJP1 / ZO-1 Guinea pig anti-Human Polyclonal Antibody
Mouse, Dog, Human
IF, IHC, IHC-Fr, WB
Unconjugated
100 µg/$589
TJP1 / ZO-1 Rabbit anti-Human Polyclonal (aa1178-1527) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TJP1 / ZO-1 Rabbit anti-Human Polyclonal (aa1570-1600) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
TJP1 / ZO-1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, IHC-Fr, WB
Unconjugated
100 µg/$854
TJP1 / ZO-1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
IF, IHC, WB
HRP Conjugated
100 µl/$1,073
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$579
TJP1 / ZO-1 Rabbit anti-Human Polyclonal (aa866-995) Antibody
Mouse, Dog, Rat, Human
IF, IHC, IHC-Fr, WB
Unconjugated
100 µg/$862
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